Franck Morceau Selected Research

Leukemia

1/2018	Autophagy as a pharmacological target in hematopoiesis and hematological disorders.
7/2016	Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia.
11/2015	Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways.
1/2015	Dual induction of mitochondrial apoptosis and senescence in chronic myelogenous leukemia by myrtucommulone A.
11/2014	Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks.
10/2013	Polyphenol tri-vanillic ester 13c inhibits P-JAK2V617F and Bcr-Abl oncokinase expression in correlation with STAT3/STAT5 inactivation and apoptosis induction in human leukemia cells.
1/2011	UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells.
12/2004	Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding.
9/2004	Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition.
4/2004	Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells.

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Franck Morceau Research Topics

Disease

13	Neoplasms (Cancer) 01/2019 - 10/2003
11	Leukemia 01/2018 - 10/2003
5	Anemia 01/2019 - 08/2006
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2015 - 01/2008
4	Inflammation (Inflammations) 01/2020 - 04/2004
3	Carcinogenesis 06/2005 - 10/2003
2	Acute Erythroblastic Leukemia (Erythroleukemia) 03/2009 - 05/2006
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2015
1	Pathologic Processes 07/2013
1	Heart Failure 01/2011
1	Epilepsy (Aura) 01/2010
1	Multiple Myeloma 08/2006
1	Urinary Tract Infections (Urinary Tract Infection) 04/2006
1	Communicable Diseases (Infectious Diseases) 04/2006
1	Asthma (Bronchial Asthma) 04/2006
1	Necrosis 10/2003

Drug/Important Bio-Agent (IBA)

8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 04/2004
4	CytokinesIBA 01/2019 - 11/2008
4	Pharmaceutical PreparationsIBA 11/2015 - 09/2004
4	Glutathione Transferase (Glutathione S-Transferase)IBA 05/2006 - 10/2003
3	Biological ProductsIBA 01/2015 - 02/2010
3	Transcription Factors (Transcription Factor)IBA 03/2009 - 10/2003
3	NF-kappa B (NF-kB)IBA 04/2006 - 10/2003
2	Proteins (Proteins, Gene)FDA Link 07/2016 - 10/2003
2	aclacinomycinsIBA 11/2014 - 03/2009
2	Erythropoietin FDA Link 11/2014 - 07/2011
2	CurcuminIBA 06/2005 - 10/2003
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 12/2004 - 10/2003
2	EnzymesIBA 09/2004 - 04/2004
1	Long Noncoding RNAIBA 01/2020
1	FlavonoidsIBA 07/2016
1	Antineoplastic Agents (Antineoplastics)IBA 07/2016
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2015
1	myrtucommulone AIBA 01/2015
1	Phosphotransferases (Kinase)IBA 10/2013
1	EstersIBA 10/2013
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2013
1	PolyphenolsIBA 10/2013
1	Erythropoietin Receptors (Erythropoietin Receptor)IBA 12/2012
1	STAT Transcription FactorsIBA 04/2012
1	Cardiac GlycosidesIBA 01/2011
1	SteroidsIBA 01/2011
1	UNBS 1450IBA 01/2011
1	heteroneminIBA 02/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2009
1	Hemin (Panhematin)FDA Link 03/2009
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2008
1	bcr-abl Fusion ProteinsIBA 01/2008
1	LactonesIBA 04/2006
1	ChalconesIBA 04/2006
1	Acetates (Acetic Acid Esters)FDA Link 09/2004
1	Glutathione (Reduced Glutathione)IBA 09/2004
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2004
1	O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA 04/2004
1	AntioxidantsIBA 04/2004
1	Phorbol EstersIBA 10/2003
1	Messenger RNA (mRNA)IBA 10/2003

Therapy/Procedure

2	Therapeutics 01/2018 - 11/2015
2	Drug Therapy (Chemotherapy) 07/2016 - 06/2005
1	Traditional Medicine (Folk Remedies) 04/2006
1	Chemoprevention 06/2005